I've always loved the land design idea of interpreting the in-game experience of leaving your sleepy small town, finding your first Pokémon partner in the tall grass or at the Pokemon Lab in town, traversing a small woodlands surrounded by Pokémon, before making it to the big city with a Gym Battle experience and Pokemon Center diner.
Then as you leave the city you can transition back into the more natural environments again before Hogsmeade.
I believe that design layout builds super naturally, represents a solid vertical slice of a Pokémon adventure from the games and anime, and allows space for all the necessary theme park-y components. (Interactive challenges a la SNW in the woods; Lab as the entrance to both/either Pokémon Snap ride or an animal / puppet show; Gym Battle a la Bowser Jr. Showdown; Pokémon Center serving themed food.)